A US-based cardiology podcast created in 2019 by Dr Amit Goyal and Dr Daniel Ambinder. It provides in-depth discussions of clinical cardiology topics, current guidelines, and expert interviews to enhance cardiology education and patient care.
Cangrelor provides rapid intravenous P2Y12 inhibition during percutaneous coronary intervention when oral treatment is unreliable, with a minimum two-hour infusion, drug-specific transition to oral agents and selective rather than routine glycoprotein IIb/IIIa inhibitor use.
Fibrinolysis for ST-elevation myocardial infarction requires clopidogrel plus parenteral anticoagulation, with important dosing changes from age 75; continued anticoagulation during transfer helps reduce recurrent ischaemic events while renal function and bleeding risk shape drug choice.
After out-of-hospital cardiac arrest, stable patients without STEMI or other high-risk features can follow delayed or selective angiography, while serial ECGs, lateral or posterior views, arrest characteristics and prognosis help identify those who still warrant earlier invasive assessment.
Coronary CT angiography answers anatomical questions, while stress echocardiography, nuclear perfusion imaging, positron emission tomography and stress cardiac magnetic resonance assess ischaemia and function. Test selection depends on pre-test likelihood, symptoms, comorbidity, exercise capacity, ECG findings and local expertise.
Right-sided congestion may reflect primary, atrial functional, ventricular functional or device-related tricuspid regurgitation. Assessment combines volume optimisation, multimodality imaging, right-heart haemodynamics and right ventricular reserve before a valve team chooses medical, surgical or transcatheter treatment.
Pregnancy planning in someone with cardiovascular symptoms or known disease requires more than a generic risk score. Symptoms, exercise tolerance, family history, lesion-specific physiology, medication safety and previous adverse pregnancy outcomes guide targeted testing, contraception advice and early multidisciplinary pregnancy heart team input.
Cardiology, acute medicine, primary-care and renal teams get a phenotype-led approach to exertional dyspnoea and congestion in patients with obesity, diabetes, atrial fibrillation, obstructive sleep apnoea and chronic kidney disease. It links symptoms, natriuretic peptides and echocardiography with diuresis, SGLT2 inhibition, cardiac rehabilitation, weight management and coordinated treatment of cardiometabolic drivers.
Cardiology, general-practice and endocrinology clinicians get a prevention-focused approach to hypertension, diabetes, obesity and early cardiac remodelling. It frames heart failure as a continuum from risk factors to structural change and symptoms, linking reliable blood-pressure measurement, urine albumin-creatinine ratio, natriuretic peptides, echocardiography and parallel cardiometabolic treatment to earlier action.
Cardiology, respiratory and critical-appraisal teams get an evidence update on intermediate-risk pulmonary embolism. It separates anticoagulation from catheter-directed thrombolysis and mechanical thrombectomy while keeping right ventricular dysfunction, biomarkers, oxygen requirement, bleeding risk, clinical deterioration endpoints, multidisciplinary PERT decisions and post-PE symptoms in view.
Cardiology, emergency and acute medicine clinicians get a focused update on recurrent angina despite non-obstructive coronary angiography. ANOCA, INOCA and MINOCA are separated clearly, with microvascular dysfunction, vasospasm, SCAD, myocarditis, Takotsubo, early cardiac MRI, risk-factor treatment and cardiac rehabilitation kept in view.
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