Clinical Problem Solvers Podcast

The Clinical Problem Solvers is a global medical education initiative dedicated to enhancing diagnostic reasoning skills among healthcare professionals. Founded in 2018, the platform offers a podcast series that delves into the intricacies of clinical problem-solving through unscripted case discussions, expert interviews, and thematic episodes.

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March 5, 2026

Episode 449: Live from Southern SGIM – Clinical Unknowns with Alec & Ann Marie

A sepsis-like collapse with cytopenias, liver failure and diarrhoea becomes much more useful when ferritin, triglycerides and fibrinogen move up the list. Open this for a sharp reminder that HLH is not the end of the diagnosis, and that chronic thrombocytopenia with hepatosplenomegaly deserves a storage-disorder work-up.

March 4, 2026

448 – RLR – Hyperkalemia

A missed dialysis session and a high potassium result can look calmer than they are. Open this for the treatment sequence: monitor early, give calcium promptly, run shift-and-elimination measures in parallel, and do not let a normal ECG or well appearance slow dialysis planning.