Primary-care, cardiology and acute medicine clinicians get a practical prescribing review of hypertension confirmation, first-line medication and low-dose combination therapy. Amlodipine-related oedema, ACE inhibitor cough or angioedema, thiazide-associated electrolyte disturbance, gout and medication intolerance are linked to mechanism-based troubleshooting and planned biochemical monitoring.

Primary-care, cardiology and nephrology clinicians get a cardiovascular risk-stratification update involving PREVENT, LDL targets, lipoprotein(a), apolipoprotein B and coronary artery calcium. The episode uses a calculate, personalise and reclassify framework to connect risk enhancers with statin and non-statin treatment decisions.

Gastroenterology, endocrinology and primary-care teams get a metabolic liver disease update. MASLD, MASH, cardiometabolic risk, fibrosis staging, FIB-4, elastography, weight-loss targets, semaglutide and resmetirom trial interpretation are linked to practical risk stratification.

Relevant to nephrology, acute medicine and ward teams managing severe hypertension, breathlessness or fluid overload in haemodialysis. It prioritises interdialytic blood pressure, dry-weight reassessment, sodium and fluid balance, while showing how medication dialysability should influence drug selection and timing.

Relevant to acute medicine, nephrology and ward teams reviewing haemodialysis patients with shortness of breath, severe hypertension, pulmonary oedema or cramps. It separates solute clearance from ultrafiltration and keeps dry weight, sodium intake, residual urine output and dialysis timing in view.

New atrial fibrillation after surgery is not just a rate problem. Confirm stability, symptoms and exertional limits, then look for pulmonary embolism, bleeding, infection, thyroid disease or electrolyte disturbance before deciding on cardioversion, anticoagulation, monitoring or discharge.

An in-flight seizure or hypoxia leaves limited equipment, patchy monitoring and a diversion decision. The practical move is early ground medical support, clear ABCs, a gathered kit station and deliberate use of nurses, paramedics or other clinicians on board.

Open this first if an abnormal blood test is easy to park. The episode makes eosinophilia a threshold-based problem: use the absolute count, screen for organ damage above 1,500 cells/µL, and think carefully before steroids when Strongyloides or malignancy remains plausible.

Palpitations after coffee are common, but this listen is really about not overreading nutrition headlines. It explains why prospective cohorts still matter, what CRAVE found on premature atrial and ventricular contractions, sleep, and activity, and why coffee advice should follow symptoms, sleep, and comorbidity.

A small plantar ulcer can hide tracking, bone involvement, or poor perfusion. Open this early if foot infections are easy to underestimate: it sharpens probe-to-bone assessment, plain radiographs first, MRI limits, and the practical point that source control and offloading matter as much as antibiotics.