The Curbsiders Internal Medicine Podcast is a popular medical education series focused on internal medicine topics. Hosted by a team of clinician educators, the podcast delivers expert interviews and discussions covering a broad range of clinical conditions, diagnostic approaches, and management strategies.
The show emphasises evidence-based medicine and practical insights, aiming to support learners at all levels—from students to practising internists—in building clinical reasoning and improving patient care.

General-practice, rheumatology and mental-health clinicians get a practical approach to nociplastic pain. Widespread pain, fatigue, poor sleep, brain fog, sensory sensitivity and overlapping pain syndromes are linked to validation, body mapping, focused exclusion testing, gradual activity, sleep treatment and cautious medication use.

Emergency, cardiology and critical-care clinicians get a resuscitation update covering unstable atrial fibrillation, stable ventricular tachycardia, refractory ventricular fibrillation and post-arrest care. Practical points include synchronised shock energy, amiodarone or procainamide, vector-change or double sequential defibrillation, vascular access and post-ROSC targets.

General practice, obstetrics and gynaecology, and sexual-health clinicians get practical menopause hormone therapy guidance. Vasomotor symptoms, genitourinary syndrome, recurrent urinary symptoms, vaginal oestrogen, transdermal oestrogen, progesterone, testosterone, contraception, bleeding review and shared decisions are central.

Primary-care, endocrinology and gastroenterology clinicians get practical nutrition counselling for diabetes, dyslipidaemia, hypertension and restrictive dieting. Mediterranean and DASH-style patterns, gradual fibre escalation, saturated-fat reduction, protein distribution and micronutrient risks are placed ahead of social-media claims and unsustainable dietary extremes.

A cardiology-facing case discussion for transient loss of consciousness, prolonged QT and ventricular tachycardia risk. It keeps cardiac sarcoidosis, non-ischaemic cardiomyopathy, cardiac MRI, FDG PET and rhythm protection linked when coronary disease does not explain the presentation.

Malignant bowel obstruction in advanced abdominal cancer needs a symptom-first approach, especially with peritoneal carcinomatosis, ascites or poor performance status. It separates reversible obstruction thinking from comfort-focused care, parenteral symptom control and honest conversations about what the patient understands.

Established ASCVD, metastatic pancreatic cancer, GLP-1/GIP endoscopy holds and levothyroxine deprescribing sit in one clinical update. The practical checks are LDL and non-HDL targets, retained gastric contents planning, honest trial-benefit discussion and reviewing low-dose thyroid replacement in older adults.

Patients asking for multi-cancer blood tests need screening, diagnostic testing and hereditary surveillance kept separate. A negative result does not rule out cancer, while a positive signal can trigger anxiety, imaging and procedures, especially without tissue-of-origin information.

Raised blood pressure is common enough to feel routine, which is why this is the best first listen. It focuses on measurement technique, validated home readings, stage 2 combination treatment, pregnancy, secondary causes and avoiding rapid treatment of asymptomatic severe readings without target-organ damage.

Heart-failure pleural effusions do not automatically need a tap when decongestion is working. The conference recap also sharpens first-pass acute liver injury tests, antibiotic step-down and inpatient medication decisions that often get prolonged by habit.