The Curbsiders Internal Medicine Podcast is a popular medical education series focused on internal medicine topics. Hosted by a team of clinician educators, the podcast delivers expert interviews and discussions covering a broad range of clinical conditions, diagnostic approaches, and management strategies.
The show emphasises evidence-based medicine and practical insights, aiming to support learners at all levels—from students to practising internists—in building clinical reasoning and improving patient care.
Preliminary signals for glucagon-like peptide-1 receptor agonists in alcohol use disorder do not replace established treatment. Practical decisions include naloxone selection, unverified methadone dosing, opioid-tolerant analgesia, flumazenil risk and transitions between injectable and sublingual buprenorphine.
Loud snoring, witnessed apnoeas, daytime sleepiness and difficult-to-control hypertension increase suspicion for obstructive sleep apnoea, but comorbidity determines the right test. Home testing suits uncomplicated high-probability cases; negative results with persistent suspicion or concern for central apnoea, hypoventilation, heart failure, opioid use or neuromuscular disease need laboratory assessment.
Cardiology, endocrinology and general-practice clinicians get a prevention-focused discussion of cardiometabolic risk, apoB, lipoprotein(a) and coronary calcium. It highlights why short-term calculators, normal HbA1c or reassuring glucose traces may understate risk in younger patients with metabolic syndrome or premature family history.
Primary-care clinicians get a structured way to discuss multivitamins, fish oil, magnesium, vitamin D, creatine and curcumin. The framework asks what the patient hopes to achieve, what evidence supports the product, how benefit will be measured and which interaction, duplication, quality or toxicity risks apply.
The internal-medicine feed carries the same clinically focused kratom discussion, reinforcing the importance of identifying the exact formulation rather than treating every product as equivalent. Routine urine drug screens may not detect exposure, and concentrated products can produce rapid withdrawal, repeated dosing and clinically important respiratory risk.
General-practice, rheumatology and mental-health clinicians get a practical approach to nociplastic pain. Widespread pain, fatigue, poor sleep, brain fog, sensory sensitivity and overlapping pain syndromes are linked to validation, body mapping, focused exclusion testing, gradual activity, sleep treatment and cautious medication use.
Emergency, cardiology and critical-care clinicians get a resuscitation update covering unstable atrial fibrillation, stable ventricular tachycardia, refractory ventricular fibrillation and post-arrest care. Practical points include synchronised shock energy, amiodarone or procainamide, vector-change or double sequential defibrillation, vascular access and post-ROSC targets.
General practice, obstetrics and gynaecology, and sexual-health clinicians get practical menopause hormone therapy guidance. Vasomotor symptoms, genitourinary syndrome, recurrent urinary symptoms, vaginal oestrogen, transdermal oestrogen, progesterone, testosterone, contraception, bleeding review and shared decisions are central.
Primary-care, endocrinology and gastroenterology clinicians get practical nutrition counselling for diabetes, dyslipidaemia, hypertension and restrictive dieting. Mediterranean and DASH-style patterns, gradual fibre escalation, saturated-fat reduction, protein distribution and micronutrient risks are placed ahead of social-media claims and unsustainable dietary extremes.
A cardiology-facing case discussion for transient loss of consciousness, prolonged QT and ventricular tachycardia risk. It keeps cardiac sarcoidosis, non-ischaemic cardiomyopathy, cardiac MRI, FDG PET and rhythm protection linked when coronary disease does not explain the presentation.
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