JAMA Clinical Reviews

JAMA Clinical Reviews is a podcast series produced by the Journal of the American Medical Association. It provides expert discussions on current clinical topics across a broad range of medical specialties.

March 10, 2026

Diagnosis and Treatment of MASLD

MASLD triage is practical when anchored to fibrosis risk rather than transaminases alone. FIB-4 from routine bloods separates low-risk patients from those needing ELF testing, elastography, or hepatology referral, while 5%, 7–10%, and 10–15% weight-loss targets map to steatosis, inflammation, and fibrosis.

March 20, 2026

Update on Peanut Allergy

Peanut allergy is diagnosed by history first, not by a positive test alone. Rapid onset after exposure, multisystem features and high-risk eczema matter most, while early regular peanut introduction and prompt epinephrine remain the practical prevention and treatment anchors.