JAMA Clinical Reviews is a podcast series produced by the Journal of the American Medical Association. It provides expert discussions on current clinical topics across a broad range of medical specialties.
Resistant hypertension should not be diagnosed from officereadings alone. Home or ambulatory monitoring, adherence review, and screening for white coat effect, obstructive sleep apnoea, and primary aldosteronism should come before further escalation, because normal potassium does not ruleout aldosteronism.
Peanut allergy is diagnosed by history first, not by a positive test alone. Rapid onset after exposure, multisystem features and high-risk eczema matter most, while early regular peanut introduction and prompt epinephrine remain the practical prevention and treatment anchors.
MASLD triage is practical when anchored to fibrosis risk rather than transaminases alone. FIB-4 from routine bloods separates low-risk patients from those needing ELF testing, elastography, or hepatology referral, while 5%, 7–10%, and 10–15% weight-loss targets map to steatosis, inflammation, and fibrosis.
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