The Neurology Minute® podcast delivers a brief daily summary of what you need to know in the field of neurology, the latest science focused on the brain, and timely topics explored by leading neurologists and neuroscientists. From the American Academy of Neurology and hosted by Stacey Clardy, MD, PhD, FAAN, with contributions by experts from the Neurology® journals, Neurology Today®, Continuum®, and more.

Neurology and geriatric teams get a focused appraisal of acetazolamide for idiopathic normal pressure hydrocephalus. Despite changes on MRI, the drug does not improve gait, cognition, quality of life or overall symptoms and causes more treatment discontinuation, reinforcing the priority of specialist shunt assessment.

Neurology, emergency medicine and critical-appraisal readers get a compact update on blood-based phosphorylated tau-217, adjunctive tirofiban after thrombolysis and thrombectomy, and artificial intelligence in peer review. The clinical thread is careful interpretation: promising biomarkers and trial signals do not yet justify stand-alone diagnosis or automatic practice change.

Emergency, acute medicine and neurology clinicians get a concise framework for separating primary from secondary headache. Abrupt onset, pattern change, systemic disease, abnormal neurology, precipitating activities and pregnancy or postpartum status are balanced against reassuring features such as longstanding recurrent attacks, symptom-free intervals and family history.

Paediatric neurology and adolescent-health teams get a concise transition-care update. Planning should begin years before transfer, using structured tools, care binders, documented responsibilities and institution-specific solutions to reduce gaps between paediatric and adult epilepsy services.

Neurology trainees, educators and critical-appraisal readers get a concise history of clinical neurology publishing. The episode connects continuous digital publication and transparent reporting with the enduring need for clinically relevant questions, robust methodology and conclusions that follow from the data.

Neurology, paediatric and adolescent-health teams get a concise care-transition update for young adults with epilepsy. It frames transition as clinical preparation rather than simple referral, with patient expectations, emotional uncertainty, medication review, seizure history and adult-service readiness all included in the handover.

Neurology, geriatrics and service-improvement listeners get a short update on prior authorisation reform in Medicare Advantage. Electronic requests, transparency, decision timelines, expedited review, oversight and the clinical consequences of administrative delay are framed as patient-care issues.

Neurology, paediatric and critical-care teams get a compact terminology and treatment update. Functional dissociative seizure terminology, focal and tonic-clonic seizure therapeutics, Dravet syndrome, NORS immunotherapy, COMBAT NORS and smartwatch-based tonic-clonic seizure detection are kept distinct.

Neurology learners get a concise classification update after the practical definition of epilepsy is met. Seizure type, epilepsy type and aetiology are separated, with focal versus generalised onset, consciousness, observable manifestations and overlapping genetic or structural causes guiding treatment planning.

Neurology, human-factors and medical-education readers get a concise consultation-skills update on Parkinson disease diagnosis. It frames uncertainty about diagnosis, treatment effects and long-term expectations as routine, and shows how explicit or implicit uncertainty can be paired with emotional acknowledgement without undermining trust.