The Neurology Minute® podcast delivers a brief daily summary of what you need to know in the field of neurology, the latest science focused on the brain, and timely topics explored by leading neurologists and neuroscientists. From the American Academy of Neurology and hosted by Stacey Clardy, MD, PhD, FAAN, with contributions by experts from the Neurology® journals, Neurology Today®, Continuum®, and more.

A short neurology and critical appraisal update on factor XIa inhibition after recent non-cardioembolic ischaemic stroke or high-risk TIA. It frames asundexian as a potential dual-pathway prevention strategy when added to antiplatelet therapy, while keeping mechanism, trial population, bleeding outcomes, approval status and current practice separate.

Stroke and acute medicine readers get a focused update on kidney injury after contrast exposure during thrombectomy pathways. Baseline renal function, intra-arterial contrast volume, risk prediction, nephrotoxin avoidance and repeat creatinine within 48 hours are the practical hooks.

A short neurology and general-practice update for chronic migraine complicated by medication overuse. It links monthly migraine days, acute medication-use days, structured education and early CGRP-targeted prevention, while noting that education was given in both trial groups.

An emergency neurology update for severe headache, acute migraine, vertigo and suspected raised intracranial pressure. It links prochlorperazine and nerve blocks with opioid avoidance, then uses STANDING, observed gait and optic nerve sheath ultrasound as bedside assessment tools.

A short specialist stroke update for teams considering right-to-left shunt in embolic stroke of undetermined source. It positions TCD as a sensitive non-invasive screen and TEE as the stronger anatomical confirmation when PFO detection will affect prevention planning.

A specialist neurodevelopmental care update for clinicians supporting patients with Rett syndrome and families. It highlights caregiver observations, communication support, active specialty mapping, rehabilitation input and planned transition from paediatric to adult services when needs evolve over time.

AAN member sections and Synapse communities are presented as year-round routes for neurology learning. Peer Q&A, protocol sharing and career advice can reduce isolated problem-solving when local answers are incomplete.

Recent DOAC use can complicate thrombolysis without stopping the stroke alert. This is a compact guide to treating anticoagulant exposure as a relative contraindication, clarifying drug and last dose early, and documenting a senior risk–benefit discussion for disabling acute ischaemic stroke.

Persistent unilateral weakness, facial droop, speech disturbance or wake-up deficit needs a broad stroke alert process. The key clinical distinction is that activation screens for time-critical assessment; it is not a severity score or proof of acute ischaemic stroke.

Older adults with gait decline, cognitive change and urinary symptoms need more than a remembered triad. The shunting review explains how imaging, temporary CSF drainage response and objective gait measures help frame referral, consent and the real risks of haematoma or low-pressure headache.