St Emlyn’s is a long-standing online resource for emergency medicine and critical care, created by a team of UK clinicians based in Manchester. The project includes a blog, podcast, and teaching materials, all focused on sharing high-quality, evidence-informed insights from the frontline of acute care.
The podcast is hosted by Prof Simon Carly and Dr Iain Beardsell.

Part 2 of the St Emlyn’s troponin special dives into high-sensitivity assays, analytical variation, delta interpretation, and the evolving NICE guidance for safer early rule-out of MI.

Simon Carley and Iain Beardsell discuss the emergency department approach to shortness of breath-covering resuscitation, early oxygen, key differentials, and a structured mental model for junior doctors.

Simon Carley and Iain Beardsell tackle the ED approach to headache-covering subarachnoid haemorrhage, meningitis, tumours, temporal arteritis, and migraine, with red flags and CT vs LP guidance.

Rick Body explains troponin’s physiology, renal clearance, timing, and early limitations of CK/LDH, introducing core concepts behind cardiac-specific assays in acute myocardial infarction.

Simon Carley and Iain Beardsell offer essential survival advice for junior doctors starting in EM, including hypothetical-deductive reasoning, red flag rule-outs, early pain relief, and when to escalate.

Simon Carley and Iain Beardsell critically examine emergency department targets in the UK-especially the 4-hour rule, trauma metrics, and financial penalties-highlighting the balance between clinical care, leadership, and measurement.

Simon Carley and Iain Beardsell break down trauma team leadership in major trauma centres-covering team roles, task allocation, CT targets, primary survey efficiency, and leadership behaviours that make resus safer.

Simon Carley and Iain Beardsell break down number needed to treat (NNT), absolute and relative risk reduction-exploring examples from thrombolysis, aspirin, and stroke trials with practical insights for shared decision-making.

When should we change practice? This episode explores the risks of early and late adoption in emergency medicine, drawing on examples like flecainide, epinephrine, VSE, and TTM.

How does prevalence affect diagnostic reasoning? This episode unpacks population risk, false negatives, test performance, shared decision-making, and the real-world impact of ‘missed’ diagnoses.