GP and Medical Educator Dr Sam Manger MBBS BSc FRACGP FASLM covers a variety of medical topics, with case studies, guideline reviews, guest interviews and more. This podcast is for medical professionals, including general practitioners, family physicians, specialists, allied health professionals, nurses, registrars/residents, medical students and anybody else who is interested in health, wellness, science and medicine.
Recurrent flushing, gastrointestinal symptoms and palpitations can prompt assessment for mast cell activation syndrome. Diagnosis involves the multisystem pattern, comparison of flare and baseline tryptase and treatment response, while management must address diagnostic uncertainty, coexisting dysautonomia and potentially harmful dietary restriction.
Asthma management from age 12 favours inhaled corticosteroid-containing treatment rather than salbutamol alone. As-needed budesonide/formoterol, maintenance and reliever therapy, inhaler technique and cumulative oral corticosteroid exposure shape prevention, while persistent exacerbations may warrant specialist assessment.
ME-CFS, POTS, hypermobility and mast cell activation syndrome can produce overlapping multisystem symptoms; careful assessment, validation without premature diagnostic confirmation, energy conservation and personalised symptom management aim to preserve capacity for activities that matter to the patient.
Food-allergy assessment begins with timing and symptom pattern rather than broad testing. Immediate immunoglobulin E-mediated reactions, delayed food protein-induced enterocolitis syndrome, cow's milk protein allergy, eczema-related sensitisation and allergic rhinitis require targeted investigation without unnecessary dietary restriction.
Safe home alcohol withdrawal depends on careful selection, recent clinical information, reliable support, pharmacy coordination, daily monitoring and clear escalation. Continuity after detoxification, rapid help following a lapse and established anti-craving medication support recovery, while glucagon-like peptide-1 receptor agonists remain unproven.
General practice, psychiatry and gynaecology teams get a practical PMDD review. Abrupt cyclical depression, rage, anxiety, panic and brain fog with symptom-free intervals should prompt direct suicide-risk assessment, cycle mapping, contraception-aware hormonal discussion and trauma-informed care.
General practice, psychiatry and obstetrics-gynaecology clinicians get a reproductive mental health review of perimenopausal anxiety, panic, irritability, low mood, fatigue and brain fog. It emphasises hormone-sensitive patterns, PMDD, postnatal history, contraception, menopausal hormone therapy risk checks and shared decision-making.
A general-practice and neurology review of ME/CFS centred on acquired functional decline and post-exertional malaise. It distinguishes delayed symptom crashes from ordinary fatigue, addresses orthostatic intolerance and diagnostic mimics, and supports pacing, adaptation, comorbidity treatment and cautious off-label prescribing.
Hypermobility is treated as a spectrum from flexibility to disabling pain and instability. This clinic-facing discussion uses Beighton scoring, historical flexibility, connective tissue features, proprioception, nociplastic sensitisation, bracing, rehabilitation and selected procedures to structure assessment and management.
A contraception request is not just method matching. Check medical eligibility first, especially migraine with aura, VTE history, mobility, age and cardiovascular risk. The same structured approach helps menopause care, intrauterine device pain planning, symptomatic discharge and self-collected screening follow-up.
.svg)