October 6, 2026
Crush injury needs tailored fluid resuscitation
Assess deficits, shock and mechanism before deciding how much fluid a patient with crush injury needs.
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Critical Appraisal
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October 5, 2026
Vasopressors need not wait for central access
A functioning short peripheral IV can start vasopressors promptly, provided the site is closely monitored.
Read briefingOctober 3, 2026
When chest pain still needs troponin
Atypical symptoms and absent risk factors do not reliably exclude myocardial infarction.
Read briefingOctober 1, 2026
Older abdominal pain needs a lower CT threshold
Minimal tenderness is less reassuring in older adults, so CT should remain readily considered.
Read briefingSeptember 30, 2026
ALS/NMD is a pattern, not a test
Mixed upper and lower motor neuron signs matter more than any single investigation when ALS is suspected.
Read briefingSeptember 27, 2026
The questions that expose clinical reasoning
Open “what” questions can uncover concerns and make clinical reasoning easier to examine.
Read briefingSeptember 23, 2026
Cooling longer after cardiac arrest adds little
TTM2 and ICECAP separate fever control from the unanswered question of whether hypothermia helps.
Read briefingSeptember 20, 2026
Does paracetamol add to morphine?
Adjunctive intravenous paracetamol may help acute pain, but the trial leaves clinically important uncertainty.
Read briefingSeptember 19, 2026
When polio stops fitting the pattern
Sensory symptoms, symmetry and age-specific incidence challenge an established diagnosis of paralytic polio.
Read briefingSeptember 18, 2026
A raised troponin is not (always) an infarction
Troponin change identifies myocardial injury; mechanism, timing and imaging determine whether it is infarction.
Read briefingSeptember 15, 2026
When anisocoria changes the differential
Light–dark comparison and associated signs help separate benign anisocoria from neurological emergencies.
Read briefingSeptember 9, 2026
Dexamethasone timing in bacterial meningitis
Early dexamethasone matters in bacterial meningitis, and Listeria confirmation may not mean it should stop.
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