September 15, 2026
When anisocoria changes the differential
Light–dark comparison and associated signs help separate benign anisocoria from neurological emergencies.
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Critical Appraisal
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Critical Appraisal
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September 9, 2026
Dexamethasone timing in bacterial meningitis
Early dexamethasone matters in bacterial meningitis, and Listeria confirmation may not mean it should stop.
Read briefingSeptember 5, 2026
Finding arrhythmias without preventing syncope
Early extended ECG monitoring finds important rhythms sooner, despite no reduction in recurrent syncope.
Read briefingAugust 30, 2026
When can paediatric pulmonary embolism testing stop?
A negative rule helps only after the child is already judged genuinely low risk.
Read briefingAugust 25, 2026
Was COPD mortality driven by steroid withdrawal?
A trial can exaggerate treatment benefit when its comparator removes established therapy.
Read briefingAugust 23, 2026
Does oseltamivir help severe influenza?
A concerning mortality signal makes routine antiviral prescribing harder to justify in critical illness.
Read briefingAugust 22, 2026
A negative trauma ultrasound cannot exclude bleeding
Prehospital ultrasound is most useful when a reliable positive finding changes the trauma response.
Read briefingAugust 18, 2026
Pulse oximetry and opioid treatment decisions
Check signal quality before escalating oxygen, and preserve maintenance treatment during acute pain.
Read briefingAugust 16, 2026
Chronic kidney disease beyond filtration
Pair eGFR with albuminuria, then frame uncertain decisions for transparent evidence appraisal.
Read briefingAugust 12, 2026
Kawasaki disease, pre-pregnancy cardiac risk, and health misinformation
Pre-pregnancy cardiac risk and Kawasaki disease, critical interpretation of endotoxin removal in septic shock and more.
Read briefingJune 7, 2026
Stroke thrombolysis, DOAC exposure and RAAS physiology
Recent anticoagulant use changes thrombolysis assessment, but it should not slow a disabling stroke alert in practice.
Read briefingApril 16, 2026
Myocarditis, coffee palpitations and leptomeningeal metastasis testing
Start with myocarditis, then use coffee palpitations and CSF tumour testing to sort out three episodes where similar findings lead to different decisions.
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