October 26, 2026
Lyme serology has two clinical blind spots
Early Lyme tests may be negative, while antibodies can remain positive long after successful treatment.
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Infectious Diseases
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Infectious Diseases
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October 23, 2026
Sexual health belongs on the acute ward
Private sexual histories can reveal risks and testing needs overlooked during an unrelated hospital admission.
Read briefingOctober 16, 2026
Glandular fever despite a negative Monospot
Distinguish Epstein–Barr virus from its mimics and advise safe recovery beyond the sore throat.
Read briefingOctober 12, 2026
Lyme disease beyond the bull's-eye rash
Recognise Lyme from expanding rashes or disseminated symptoms, even without a remembered tick bite.
Read briefingOctober 2, 2026
When microbiology results mislead treatment
CRP, dipsticks and cultures need clinical context before they change antibiotic treatment.
Read briefingSeptember 19, 2026
When polio stops fitting the pattern
Sensory symptoms, symmetry and age-specific incidence challenge an established diagnosis of paralytic polio.
Read briefingSeptember 17, 2026
Back pain before the weakness starts
Spinal epidural abscess can be advanced before fever or neurological deficits appear.
Read briefingSeptember 9, 2026
Dexamethasone timing in bacterial meningitis
Early dexamethasone matters in bacterial meningitis, and Listeria confirmation may not mean it should stop.
Read briefingAugust 29, 2026
Endocarditis starts before the echocardiogram
Classical signs may be absent; culture volume and device-aware imaging carry more diagnostic weight.
Read briefingAugust 23, 2026
Does oseltamivir help severe influenza?
A concerning mortality signal makes routine antiviral prescribing harder to justify in critical illness.
Read briefingAugust 14, 2026
HIV harm reduction, tricuspid regurgitation and atypical parkinsonism
HIV harm reduction and tricuspid valve assessment with neurological diagnostic uncertainty, rheumatic fever and cancer nutrition
Read briefingAugust 3, 2026
Polymyalgia rheumatica, antimicrobial choices, bronchiectasis and burns
A busy Monday spans evolving polymyalgia rheumatica, structured antimicrobial selection, bronchiectasis and burn coverage.
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